MiRNAs have been recently have and discovered been proven to be involved in various processes in animals. Through new state-of-the-art techniques the authors demonstrate that one particular miRNA recognizes and regulates the translation of the gene time clock. This constitutes the initial example of a precise miRNA-gene regulation in the central time clock. Even more importantly Perhaps, the researchers were one of the primary to show that there surely is a clear function of miRNA regulation in the mind generally and behavior specifically..-We looked at Lin28b in a variety of ways in mice to review its effects on cancers, from increasing it significantly to deleting it, – stated Dr. Zhu, co-senior author of the paper. -From this and earlier studies, it would appear that Lin28b activates the metabolic pathways offering the inspiration of growth for several cancers. – The next phase for the Zhu lab is to determine whether genes linked to Lin28b have equivalent effects on the advancement of cancer, and to determine if those genes could be more effective targets for potential therapies.
Argos’ AGS-003 in conjunction with sunitinib demonstrates favorable PFS for renal cell carcinoma Argos Therapeutics announced that its Arcelis immunotherapy for renal cell carcinoma , AGS-003, demonstrated favorable progression-free survival and protection in combination with sunitinib, based on updated results from a continuing Stage 2 trial.