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Released in Oncogene, current research from the the laboratory of Prof. Avri Ben-Ze’ev of the Section of Molecular Cell Biology shows that the tumor cells at the invasive front of later-stage individual colorectal cancer may take a straight bigger step back: Some of their gene expression patterns are shared with those of healthful intestinal stem cells. Colorectal cancer is usually most deadly when the tumor has metastasized – spread to various other organs in the body, mainly to the liver. Prof. Ben-Ze’ev and his group had previously found that a mutation within 80 percent of most colorectal cancers network marketing leads to enhanced expression of another gene, L1, especially in the cells at the industry leading of metastatic growth. L1 is known to are likely involved in cell-to-cell adhesion; in the present study, further investigation into L1 expression led the group to just one more gene: SMOC-2.