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Anoxia-induced suspended animation helps survive hypothermia How could it be that some individuals who apparently freeze to loss of life, with no heart rate or respiration for extended periods, could be brought back alive without long-term negative health consequences? New findings from the laboratory of cell biologist Mark B. Roth, Ph.D., of Fred Hutchinson Cancers Research Center, may help explain the mechanics behind this broadly documented phenomenon. Reporting online prior to the July 1 print issue of Molecular Biology of the Cell, Roth, an associate of the Hutchinson Center’s Basic Sciences Division, and co-workers show that two widely divergent model organisms – yeast and nematodes, or garden worms – can survive hypothermia, or potentially lethal cold, if they are first put into a continuing state of suspended computer animation by means of anoxia, or intense oxygen deprivation.