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Study boosts the list of CBD-fighting drugs

A prestigious study by researchers from Harvard Medical School (HMS) examining clinical trials supporting CBD as an anti-psychotic medicine has helped policymakers and business leaders to completely shift gears and significantly boost the list of drugs with demonstrated anti-psychotic properties.

The study, which focused on THC, the main psychoactive compound in cannabis, was published in Nature Scientific Reports. The authors claim their study helped prompt the Federal Drug Administration (FDA) to schedule CBD as an indication for treating severe problems caused by mental illness such as schizophrenia, major depression, and anxiety.

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Can material science technique successfully treat degenerative brain disease?

A material science techniques developed for developing flexible bioelectronic computer chips have been successfully demonstrated.

This breakthrough in material science developed by a team led by Dr Xinceng Qi, from Huangbo University, and Prof Dr Thughan Hu, from Indiana University has been published in eLife. It is a participant in the Bisided 2011 contest titled “Material Science for Computing Technology and Healthcare” and is featured on major one-page spread in the scientists’ latest journal issue, “Encoding EM-microscopic devices to make miniaturized chips. ” The team is the first in the field to demonstrate its materials science method doing real-world applications.

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JAK inhibitors may slow progression of COPD

A compound approved to treat atopic dermatitis may slow the progression of chronic obstructive pulmonary disease (COPD), an irreversible condition marked by inflammation and narrowing of airways. JAK inhibitors were first FDA-approved to treat the condition in adults with a rare genetic form of the disease.

The researchers created a post-streptococcal viral infection (inflamed myocardial scar and/or chronic obstructive pulmonary disease/cOPD) model system containing human JAK2-109. They created a conditional knockout of the JAK2 gene caused by infection with the Mycotoxin Kinase 2 (MKK2) bacteria. These cells express the MKK2 protein which is required for the lungs to heal. The engineered cells have no functional version of the gene. Expression of the special protein has prevented detection of JAKs or expression of specific human proteins that are involved in helping to safeguard the lung. After treatment with JAK inhibitors, MKK2-109 cells were reactivated. In response, the lungs of mice whose lungs have not been acclimated to JAK activation showed less inflammation, less narrowing, and less inflammation of the small airways.

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Doctors Around the World Welcomes Green Such as Bwana to Chicago Nurses Committee

On Friday, April 2, Breastfeeding advocates—celebrated during the Green March on Chicago, C. S. C. — celebrated along with/reached out to the local Chicago nurses network. With the encouragement of the C. S. C., a team of eight Chicago nurses working to support the city of 200, 000 will assist Chicago Public Health’s Hygiene and HygieneLab® (HHL) Green Line, which has started accepting patients from the hospital community through collaborations such as the Walk-Free Center, outdoor events such as yoga sessions and coffee mornings, outdoor concerts to serve the fans and the public, and more.

“When we were looking for 50 nurses to show solidarity at this event, none came forward and we were right there, which was an amazing and inspiring moment, ” said Diana Costa-Areten, M. D., the founder and director of the C. S. C. “We saw ourselves and our staff as allied and with Chicago Public Health. We think about ourselves as some of our neighbors and colleagues. ”

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New method validates fasting cell indicator

Researchers have developed a technology capable of verifying whether a single slice of lead-acid-based glass collect a driven or non-driven test tube runs. Thoroughly testing basic functions is the immediate future of the research into artificial intelligence (AI) and research concerning regular dietary shifts related to success.

Xinqiang Dong, Head of the Biomedical Artificial Intelligence Laboratory under the Ministry of Science, I. T. and the Institute of Diagnostics of the Chinese Academy of Sciences (CAS), at the center of the work of Zhang Chun and Xianguo Shen, has strengthened the capability to produce continuous and reliable data in promising conditions in laboratory laboratories. The work was recently published in Nanoscale on Artificial Intelligence (NAI), a peer-reviewed journal of the Chinese Academy of Sciences.

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Focus, Loneliness and Disandonment Linked to Greater Risk of Developing Depression

People who display higher levels of emotional engagement, especially in early childhood, are 80% more likely to develop depression later in life and are more likely to experience social isolation, destructive emotions or trauma (New England Journal of Medicine, 2019). “This study is the first step in developing new and potentially better treatments for depression. Depression prolonged by negative affect has become a public health crisis, ” said senior author Dr. Jessica McCuise of Raleigh, N. C., who earned her medical degree in psychology and ethic embryology. She is the Isabella E. Burt Professor of Human Development and Family Growth and the Rodger W. and Barbara L. Vennin Professor of Developmental Psychology at the University of North Carolina in Chapel Hill. “We need to begin by recognizing, between and across individuals, which affect patterns of depressive symptoms that are associated with lower levels of physical activity and spending time outdoors. ”

McCuise and her associates used National Institutes of Health grant to assess childhood performance on sustained brief timed bicycle exercise, estimated respiratory fitness, and health outcomes in young children and adolescents. Using data from the JAD Kids Study, a longitudinal cohort study, the researchers identified the mental health scores of sixteenth to eighteenth-age children—32 studies were included in the meta-analysis of data from 46, 300 children in 6th grade in the US, UK, Cuba, Israel, Germany, China and Russia.

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Scientists develop novel imaging technique that could improve early detection of Alzheimer"s

In the search for a breakthrough in Alzheimer’s disease diagnosis and treatment, Johns Hopkins researchers have engineered a novel, nondestructive, wearable, and low-cost material for rapidly measuring acetylcholine, a neurotransmitter that promotes neuronal connections.

Research published in the March 2020 issue of Science Advances, the study is the first to report a wearable, commercially available, and simple to use tool for measuring acetylcholine, when administered intravenously.

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New study links synapse loss and survival to unravel elusive Alzheimer"s treatments

While synaptic connections are essential for maintaining communication between neurons, Alzheimer’s Disease (AD) has become the most common neurodegenerative disease. People with AD develop gradual loss of synaptic connections between different brain regions, eventually leading to the loss of memory and personality. Your brain needs these connections to carry out necessary information related to perception, movement, thinking and memory. Without synaptic connections, your brain cannot communicate effectively with other brain regions, including your motor cortex. Blind mice, for example, cannot rapidly control their bladder with their paws. Monday, a 6-month study published in Nature Neuroscience will air the connection between synaptic connections in AD and how this affects memory.

“Our study has very high potential to impact scientists involved in clinical care of patients with cognitive, behavioral and attention disorders to make the vision of a person’s brain better, ” said Dawood Shafiee, Ph. D., research fellow in neuroscience in the Department of Life Sciences, University of Chicago. Shafiee, who has received funding from the National Institute of Mental Health, the National Institute of Aging, the National Institute of Neurological Disorders and Stroke (NINDS), and the National Institute of Health and Developmental Technologies, is the principal investigator of the study.

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Implant surface repair shows early promise in MS

When Elena Mecour, a recent doctoral graduate of the McGill University Health Centre (MUHC), has repeatedly spent hours repairing her retina, her sinus and the part of her brain that processes speech, no one knew she would be able to perform such an intricate and complex repair.

“I had such a difficult time reproducing the repairs that I finally decided to do it, ” says Elena, who completed the training in Israel, in which she was also adapted to a subcontinent, underletic conditions without sunlight-induced hearing loss.

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Americans with Disabilities Under Threat From Asbestos Shortage

* DISABILITY is being driven by greater access to specialties that offer the highest level of medical care. These include asthma, certain allergies, and conditions that affect blood circulation, heart, lungs, cardiovascular systems, and nerves. For these patients, health care providers are becoming reliant on patients to also address vocational competency, pay for personal transportation, and navigate dietary challenges. Jesus Campos, MD, FACS, investigator in pulmonary medicine and pulmonary science at Michigan Medicine, says even more resources are needed, particularly for patients and families with disabilities and chronic diseases. “What’s happening is that the acute era of medicine is being replaced by more research-based medicine in our society. Our clinical program is evolving and evolving, but I’m not optimistic yet, ” said Campos, who is also Heinz Endowed Professor of Pulmonary Medicine at Michigan Medicine. “The public health impact of these changes is what I think healthcare practitioners need to know about and document even though most organizations have already done so, ” he said.

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ACIP approves intervention for HIV-associated complacency in adults

Health advocacy group Accipirate, one of the largest inpatient vaccination and treatment facilities in the Midwest, announced on Friday a new initiative aimed at addressing complacency among residents who have sex with HIV.

“We now have a new approach to effectively eradicate HIV, and if we see a continuation of complacently HIV-negative participants — including in such-low-risk populations as same-sex couples — we can act on it and eliminate it, ” said Rudela Pedigo, M. D., President of Accipirate, in a Presentation at the International AIDS Conference in Mekong city, South Korea.

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Scientists discover genetic biomarker in blood to detect aggressive endometrial cancer

Scientists at the Centenarian Breast Center of Nova Scotia (CBC) have discovered a genetic biomarker to aid methods to detect aggressive endometrial cancer (EGCLC). This finding, published in the journal Thorax, will help doctors deliver the optimal treatment to patients. CBC Chief Scientific Officer and Professor Leslie Siemers says, “The discovery of this promising new tool is truly humbling and it will have a tremendous impact on cancer screening in our population. It will allow us to detect those cancer cells which are really aggressive and become resistant to the standard of care. ” This new gene-guided tool will be a valuable addition to the Centenarian Breast Center’s blood testing program and will enable doctors to detect early-stage cancer in the prevention.

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US military ventilator orderable for PPE starts September 1st, Amazon Plans Twitter account added

The US Department of Defense has awarded a $400 million contract for medical-grade ventilators to the Army Corps of Engineers for personal protective equipment (PPE) using the same technology used in ER-biohazard suits used in hospitals in the world’s first mass-produced ventilators.

The new order comes over 2 years after the Department of Defense had spent about $1 billion for such machines, which are simpler to produce.

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Research Highlights from the 24th ACR/ARHP Annual Meeting

The 24th Annual Conference of the American College of Rheumatology (ARC) will be held March 24–26, 2019, in New Orleans, LA. ARC is one of the largest ever events held within the US and currently one of the largest examinations in the world of assigned studs. The ACR is the leading source of research information for rheumatologists, endocrinologists, and haematologists, covering a broad range of musculoskeletal diseases including rheumatoid arthritis, osteoarthritis, lupus, psoriasis and Graves’ disease. As clinicians and researchers, the members of the American College of Rheumatology are encouraged to participate in the three-day conference, supported by the National Institutes of Health and the American College of Rheumatology Foundation. Russell Rosen, MD, RIA, will address the 3-day session entitled, “Progress on treatment of rheumatoid arthritis and lupus and attendant disorders, ” which provides a general overview of the field. “The ACR Congress aims to provide a forum to disseminate academic articles and best practice. The conference will also provide a forum for all rheumatologists and their collaborators to share best practices and innovations in rheumatology. ”

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Drug patch may treat chimpanzees with brain disorder

A research team led by UCLA scientists has developed a drug patch, or nanobody, that can treat behavioral problems caused by mutations in certain genes present in chimpanzees, protecting them from deadly brain infections.

The nanobody, called PangolFM, has been approved by the U. S. Food and Drug Administration and successfully tested on chimpanzees with rhabdomyosarcoma, a severe, inherited disease that damages the skin and causes swelling and pain. Even with two brains, the researchers observed no brain damage or deaths.

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When Wellness Musclesakened, Muscle Eaters Lose Their Torques

As a body coach, I hear a lot about the benefits of exercising your hips, a natural response that we get as men after menopause. And there’s a lot to know about your self-assessment and how you’re doing on that.

“I imagine a lot of women are saying: ‘I can’t remember the last time I did an exercises, ’ or when I had my limits, ’ or when the first thing I did was yoga, ” says Patti Linsenmeyer, a fellow nutrition coach at the City of Hope clinic.

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What Color Lipids Will Provide When Used together

In a new article published in the Journal of Lipid Research, University of Alberta scientists report the results of a study evaluating the impact of the color compounds that can coat white fat cells. The researchers found that the combination therapy increased energy expenditure and enhanced lipids production in certain patients who are sensitive to dietary lipids. Their findings suggest that the approach may offer novel strategies against a number of metabolic disorders.

According to Min Cheng of the Department of Pharmacology and Therapeutics at the Medical College of Northern Alberta, the results of the study supported the use of memethicone as a possible route to prevent the development of obesity-related insulin resistance in mice. The study also showed that memethicone prevented abnormal changes in fat subcutaneous cells known as beta-cells, an important locus for suppressing the growth of adipocytes and inducing insulin resistance in obesity-related Type 2 diabetes.

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